منابع مشابه
Physiology of Growth Hormone Secretion
Growth hormone (GH) is secreted in a pulsatile fashion from the anterior pituitary gland. The synthesis and the secretion of GH are regulated mainly by two hypothalamic neuropeptides, the growth hormone-releasing hormone (GHRH) and somatostatin. A wide variety of physiologic and hormonal factors exert an effect on GH secretion. This paper will review physiology of GH secretion and the factors t...
متن کاملPeriplasmic secretion of human growth hormone by Escherichia coli.
The gene coding for human growth hormone (hGH) was fused to the coding sequence for the signal peptide of a secreted Escherichia coli protein. STII heat-stable enterotoxin. This hybrid gene was expressed in E. coli. The signal peptide is properly processed and hGH is secreted in to the periplasmic space. In E. coli, some of the material made is proteolytically clipped or deamidated. The effect ...
متن کاملSuppression of human growth hormone secretion by melatonin and cyproheptadine.
Pituitary growth hormone (GH) release in the rat is stimulated via serotoninergic pathways and can be inhibited by treatment with compounds that act as serotonin antagonists, such as cyproheptadine or the pineal gland hormone, melatonin. To investigate a possible role for serotonin in the control of human GH release, the effects of cyproheptadine and melatonin administration on the GH responses...
متن کاملRegulation of human growth hormone secretion and its disorders.
Growth hormone (GH) secretion from anterior pituitary is regulated by the hypothalamus and the mediators of GH actions. Major regulatory factors include GH releasing hormone (GHRH), somatostatin (SRIF), GH releasing peptide (ghrerin) and insulin-like growth factor (IGF-I). The principal physiological regulation mechanisms of GH secretion are neural endogenous rhythm, sleep, stress, exercise, an...
متن کاملTests for growth hormone secretion.
Tests for growth hormone secretion SIR,-We were interested in the correspondence between Dr Addy and Professor Brook and Dr Hindmarsh on detecting organic illness through assessment of height velocity .' 2 The question, however, is academic and their arguments theoretical since, as we have recently shown, the assessment of height velocity in individuals is so imprecise as to be clinically meani...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1972
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19720037